Terra-Cortril Side Effects, and Drug Interactions - Oxytetracycline and Hydrocortisone

Terra-Cortril Side Effects, and Drug Interactions - Oxytetracycline and Hydrocortisone

SIDE EFFECTS

Allergic reactions due to individual hypersensitivity including contact dermatitis may occur but are rare.

Reactions occurring most often from the presence of the oxytetracycline are allergic sensitizations.

Increased Lacrimation, a transient stinging or burning sensation, and a foreign body sensation have been reported occasionally with opthalmic tetracycline products.

The reactions due to the steroid component in decreasing order of frequency are: elevation of intraocular pressure with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation, and delayed wound healing.

Should signs of local irritation occur, discontinue treatment immediately.

Elevation of intraocular pressure - see “Warnings”.

Secondary infection: The development of secondary bacterial or fungal infection has occurred after use of combinations containing steroids and antimicrobials.

Fungal infections of the cornea are particularly prone to develop coincidentally with long-term applications of steroid. With long-term applications of steroids, the cornea is particularly prone to develop fungal infections. The possibility of fungal invasion must be considered in any persistent corneal ulceration where steroid treatment has been used.

Secondary bacterial ocular infection following suppression of host responses also occurs.

The use of Terra-Cortril Eye/Ear Suspension with Polymixin B and Terra-Cortril Eye/Ear ointment with Polymixin B should be discontinued if such reactions occur.

DRUG INTERACTIONS

No information available.