Talwin Compound Overdose, Contraindications and Information - Pentazocine and Aspirin

Talwin Compound Overdose, Contraindications and Information - Pentazocine and Aspirin

OVERDOSE

Manifestations:  Clinical experience with pentazocine overdosage has been insufficient to define the signs of this condition. Signs of salicylate overdosage include headache, dizziness, confusion, tinnitus, diaphoresis, thirst, nausea, vomiting, diarrhea, tachycardia, tachypnea, Kussmaul breathing, convulsions, and coma. Death is usually from respiratory failure.

Treatment:   Treatment for overdosage of TALWIN Compound, should include treatment for salicylate poisoning as outlined in standard references.

Oxygen, intravenous fluids, vasopressors, and other supportive measures should be employed as indicated. Assisted or controlled ventilation should also be considered. For respiratory depression due to overdosage or unusual sensitivity to pentazocine, parenteral naloxone is a specific and effective antagonist.

TALWIN Compound should not be administered to patients who are hypersensitive to either pentazocine or salicylates, or in any situation where aspirin is contraindicated.