Requip Online, Description, Chemistry, Ingredients - Ropinirole

Requip Online, Description, Chemistry, Ingredients - Ropinirole

DESCRIPTION

Requip (ropinirole hydrochloride), an orally administered anti-Parkinsonian drug, is a non-ergoline dopamine agonist. It is the hydrochloride salt of 4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one monohydrochloride and has an empirical formula of C ₁₆ H ₂₄ N ₂ O·HCl. The molecular weight is 296.84 (260.38 as the free base).  The structural formula is:

Ropinirole hydrochloride is a white to pale greenish-yellow powder with a melting range of 243° to 250°C and a solubility of 133 mg/mL in water.

Each pentagonal film-coated Tiltab® tablet with beveled edges contains ropinirole hydrochloride equivalent to ropinirole, 0.25 mg, 0.5 mg, 1 mg, 2 mg, 4 mg or 5 mg. Inactive ingredients consist of: croscarmellose sodium, hydrous lactose, magnesium stearate, microcrystalline cellulose, and one or more of the following: FD&C Blue No. 2 aluminum lake, FD&C Yellow No. 6 aluminum lake, hydroxypropyl methylcellulose, iron oxides, polyethylene glycol, polysorbate 80, titanium dioxide.