Maxalt Online, Description, Chemistry, Ingredients - Rizatriptan

Maxalt Online, Description, Chemistry, Ingredients - Rizatriptan

DESCRIPTION

MAXALT® (RIZATRIPTAN BENZOATE) TABLETS

MAXALT-MLT™ (RIZATRIPTAN BENZOATE) ORALLY DISINTEGRATING TABLETS

MAXALT contains rizatriptan benzoate, a selective 5-hydroxytryptamine_1B/1D (5-HT_1B/1D) receptor agonist. Rizatriptan benzoate is described chemically as: N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine monobenzoate. Its empirical formula is C₁₅H₁₉N₅•C₇H₆O₂, representing a molecular weight of the free base of 269.4. Rizatriptan benzoate is a white to off-white, crystalline solid that is soluble in water at about 42 mg per mL (expressed as free base) at 25°C. MAXALT® Tablets and MAXALT-MLT™ Orally Disintegrating Tablets are available for oral administration in strengths of 5 and 10 mg (corresponding to 7.265 mg or 14.53 mg of the benzoate salt, respectively). Each compressed tablet contains the following inactive ingredients: lactose monohydrate, microcrystalline cellulose, pregelatinized starch, ferric oxide (red), and magnesium stearate. Each lyophilized orally disintegrating tablet contains the following inactive ingredients: gelatin, mannitol, glycine, aspartame, and peppermint flavor.