A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Thyrel Trh Side Effects, and Drug Interactions - Protirelin
Thyrel Trh Side Effects, and Drug Interactions - Protirelin
SIDE EFFECTS
Side effects have been reported in about 50% of the patients tested with Thyrel
TRH. Generally, the side effects are minor, have occurred promptly, and have
persisted for only a few minutes following injection.
Cardiovascular reactions:
Marked changes in blood pressure, including both hypertension and hypotension
with or without syncope, have been reported in a small number of patients.
Endocrine reaction:
Breast enlargement and leakage in lactating women for up to two or three days.
Other reactions:
Headaches, sometimes severe, and transient amaurosis in patients with pituitary
tumors. Rarely, convulsions may occur in patients with predisposing conditions,
e.g., epilepsy, brain damage. Nausea; urge to urinate; flushed sensation; lightheadedness;
bad taste in mouth; abdominal discomfort; and dry mouth. Less frequently reported
were: Anxiety; sweating; tightness in the throat; pressure in the chest; tingling
sensation; drowsiness; and allergic reactions.
Pituitary apoplexy requiring acute neurosurgical intervention has been reported
infrequently for patients with pituitary macroadenomas following the acute administration
of protirelin injection in the setting of combined anterior pituitary function
testing in conjunction with LHRH and insulin.
DRUG INTERACTIONS
No Information Provided.
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