A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Prevpac Online, Description, Chemistry, Ingredients - Lansoprazole, Amoxicillin And Clarithromycin
Prevpac Online, Description, Chemistry, Ingredients - Lansoprazole, Amoxicillin And Clarithromycin
DESCRIPTION
To reduce the development of drug-resistant bacteria and maintain the effectiveness of
PREVPAC and other antibacterial drugs, PREVPAC should be used only to treat or prevent infections
that are proven or strongly suspected to be caused by bacteria.
THESE PRODUCTS ARE INTENDED ONLY FOR USE AS DESCRIBED. The individual products
contained in this package should not be used alone or in combination for other
purposes. The information described in this labeling concerns only the use of
these products as indicated in this daily administration pack. For information
on use of the individual components when dispensed as individual medications
outside this combined use for treating Helicobacter pylori (H. pylori) ,
please see the package inserts for each individual product.
PREVPAC consists of a daily administration pack containing two PREVACID 30-mg
capsules, four amoxicillin 500-mg capsules, USP, and two clarithromycin 500-mg
tablets, USP, for oral administration.
PREVACID ® (lansoprazole) Delayed-Release Capsules
The active ingredient in PREVACID capsules is a substituted benzimidazole,
2-[[[3-methyl-4- (2,2,2-trifluoroethoxy)-2- pyridyl] methyl]sulfinyl] benzimidazole,
a compound that inhibits gastric acid secretion. Its empirical formula is C
16 H 14 F 3 N 3 O 2 S
with a molecular weight of 369.37. The structural formula is:
Lansoprazole is a white to brownish-white odorless crystalline powder which
melts with decomposition at approximately 166°C. Lansoprazole is freely soluble
in dimethylformamide; soluble in methanol; sparingly soluble in ethanol; slightly
soluble in ethyl acetate, dichloromethane and acetonitrile; very slightly soluble
in ether; and practically insoluble in hexane and water.
Each delayed-release capsule contains enteric-coated granules consisting of
lansoprazole (30 mg), hydroxypropyl cellulose, low substituted hydroxypropyl
cellulose, colloidal silicon dioxide, magnesium carbonate, methacrylic acid
copolymer, starch, talc, sugar sphere, sucrose, polyethylene glycol, polysorbate
80, and titanium dioxide. Components of the gelatin capsule include gelatin,
titanium dioxide, D&C Red No. 28, FD&C Blue No. 1, and FD&C Red
No. 40.
TRIMOX ® (amoxicillin, USP)
Amoxicillin, USP, (2 S ,5 R ,6 R )-6-[( R )-(-)-2-Amino-2-(
p -hydroxyphenyl) acetamido]-3, 3-dimethyl-7-oxo-4-thia-1- azabicyclo[3.2.0]heptane-2-carboxylic
acid trihydrate, is a semisynthetic penicillin, an analogue of ampicillin. It has the following chemical structure:
The empirical formula is C 16 H 18 N 3 O 5
S · 3H 2 O, and the molecular weight is 419.45.
The maroon and light-pink capsules contain amoxicillin trihydrate equivalent
to 500 mg of amoxicillin. The inactive ingredient in the capsules is magnesium
stearate.
BIAXIN ® Filmtab ® (clarithromycin tablets, USP)
Clarithromycin is a semi-synthetic macrolide antibiotic. Chemically, it is
6- 0 -methylerythromycin. The molecular formula is C 38 H
69 NO 13 , and the molecular weight is 747.96. The structural formula is:
Clarithromycin is a white to off-white crystalline powder. It is soluble in
acetone, slightly soluble in methanol, ethanol, and acetonitrile, and practically
insoluble in water.
Each yellow oval film-coated immediate-release tablet contains 500 mg of clarithromycin
and the following inactive ingredients: hydroxypropyl methylcellulose, hydroxypropyl
cellulose, colloidal silicon dioxide, croscarmellose sodium, D&C Yellow
No. 10, magnesium stearate, microcrystalline cellulose, povidone, propylene
glycol, sorbic acid, sorbitan monooleate, titanium dioxide, and vanillin.
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