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Condylox Side Effects, and Drug Interactions - Podofilox

SIDE EFFECTS

In clinical trials with Condylox® Gel 0.5%, the following local adverse reactions were reported during the treatment of anogenital warts. The severity of local adverse reactions were predominantly mild or moderate and did not increase during the treatment period. Severe reactions were most frequent within the first 2 weeks of treatment.

Adverse Reaction	Mild	Moderate	Severe
Inflammation	32.2%	30.4%	9.3%
Burning	37.1%	25.9%	11.5%
Erosion	27.0%	20.8%	8.9%
Pain	23.7%	20.4%	11.5%
Itching	32.2%	16.0%	7.8%
Bleeding	19.2%	3.0%	0.7%

Other local adverse reactions reported included stinging (7%), and erythema (5%); less commonly reported local adverse events included desquamation, scabbing, discoloration, tenderness, dryness, crusting, fissures, soreness, ulceration, swelling/edema, tingling, rash, and blisters.

The most common systemic adverse event reported during the clinical studies was headache (7%).

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