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Nembutal Indications, Dosage, Storage, Stability - Pentobarbital

Nembutal Indications, Dosage, Storage, Stability - Pentobarbital

INDICATIONS

Oral

Sedatives.
Hypnotics, for the short-term treatment of insomnia, since they appear to lose their effectiveness for sleep induction and sleep maintenance after 2 weeks (See CLINICAL PHARMACOLOGY section).
Preanesthetics.

DOSAGE AND ADMINISTRATION

Adults: The usual hypnotic dose consists of 100 mg at bedtime.

Children: The preoperative dose is 2 to 6 mg/kg/24 hours (maximum 100 mg), depending on age, weight, and the desired degree of sedation.

The proper hypnotic dose for children must be judged on the basis of individual age and weight.

Dosages of barbiturates must be individualized with full knowledge of their particular characteristics and recommended rate of administration. Factors of consideration are the patient’s age, weight, and condition.

Special patient population: Dosage should be reduced in the elderly or debilitated because these patients may be more sensitive to barbiturates. Dosage should be reduced for patients with impaired renal function or hepatic disease.

HOW SUPPLIED

NEMBUTAL Sodium Capsules (pentobarbital sodium capsules, USP) are supplied as follows:

50 mg transparent and orange-colored capsules (imprinted with a and the Abbo-Code CF) in bottles of 100 (NDC 0074-3150-11).

100 mg yellow capsules (imprinted with a and the Abbo-Code CH) in bottles of 100 (NDC 0074-3114-01), and in the Abbo-Pac® unit dose packages of 100 (NDC 0074-3114-21).

Recommended storage: Store below 86° F (30° C).

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