A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Nembutal Online, Description, Chemistry, Ingredients - Pentobarbital
Nembutal Online, Description, Chemistry, Ingredients - Pentobarbital
DESCRIPTION
NEMBUTAL® (PENTOBARBITAL SODIUM CAPSULES), USP
WARNING—MAY BE HABIT FORMING
The barbiturates
are nonselective central
nervous system
depressants which are primarily used as sedative
hypnotics. The barbiturates
and their sodium salts are subject
to control under the
Federal Controlled Substances Act (See ADVERSE
REACTIONS: DRUG ABUSE AND DEPENDENCE subsection).
Barbiturates are substituted pyrimidine
derivatives in which the basic structure common to these drugs is
barbituric acid, a substance
which has no central
nervous system
(CNS) activity. CNS activity
is obtained by substituting alkyl, alkenyl, or aryl groups on the
pyrimidine ring.
Nembutal (pentobarbital
sodium) is chemically represented by sodium
5-ethyl-5-(I-methylbutyl) barbiturate.
The sodium salt
of pentobarbital
occurs as a white, slightly bitter powder which is freely soluble
in water and alcohol
but practically insoluble in benzene
and ether. Nembutal
Sodium capsules for oral
administration contain either 50 mg
or 100 mg of pentobarbital
sodium.
Inactive Ingredients
50 mg Capsule:
FD&C Blue No.1, FD&C Red No.3, FD&C Yellow No.6, gelatin,
lactose, magnesium
stearate, polacrilin potassium and potassium
chloride.
100 mg Capsule:
colloidal silicon
dioxide, corn starch, FD&C
Blue No.1, FD&C Red No.3, FD&C Yellow No.5 (tartrazine),
FD&C Yellow No.6, gelatin, magnesium
stearate and potassium
chloride.
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