A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Pediotic Side Effects, and Drug Interactions - Neomycin,Polymyxin B and Hydrocortisone
Pediotic Side Effects, and Drug Interactions - Neomycin,Polymyxin B and Hydrocortisone
SIDE EFFECTS
Neomycin occasionally causes skin sensitization. Ototoxicity and nephrotoxicity
have also been reported (see WARNINGS ). Adverse reactions have occurred with
topical use of antibiotic combinations including neomycin and polymyxin B. Exact
incidence figures are not available since no denominator of treated patients
is available. The reaction occurring most often is allergic sensitization. In
one clinical study, using a 20% neomycin patch, neomycin-induced allergic skin
reactions occurred in two of 2,175 (0.09%) individuals in the general population.
1 In another study, the incidence was found to be approximately 1%.
2
The following local adverse reactions have been reported with topical corticosteroids,
especially under occlusive dressings: burning, itching, irritation, dryness,
folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral
dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection,
skin atrophy, striae, and miliaria. Stinging and burning have been reported
rarely when this drug has gained access to the middle ear.
DRUG INTERACTIONS
No Information Provided.
top
