A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Pediotic Online, Description, Chemistry, Ingredients - Neomycin,Polymyxin B and Hydrocortisone
Pediotic Online, Description, Chemistry, Ingredients - Neomycin,Polymyxin B and Hydrocortisone
DESCRIPTION
PEDIOTIC Suspension (neomycin and polymyxin B sulfates and hydrocortisone otic
suspension) is a sterile antibacterial and anti-inflammatory suspension for
otic use. Each mL contains: neomycin sulfate equivalent to 3.5 mg neomycin base,
polymyxin B sulfate equivalent to 10,000 polymyxin B units, and hydrocortisone
10 mg (1%). The vehicle contains thimerosal 0.001% (added as a preservative)
and the inactive ingredients cetyl alcohol, glyceryl monostearate, mineral oil,
polyoxyl 40 stearate, propylene glycol, and Water for Injection. Sulfuric acid
may be added to adjust pH. PEDIOTIC Suspension has a minimum pH of 4.1, which
is less acidic than the minimum pH of 3.0 for CORTISPORIN® Otic Suspension.
Neomycin sulfate is the sulfate salt of neomycin B and C, which are produced
by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae).
It has a potency equivalent of not less than 600 µg of neomycin standard per
mg, calculated on an anhydrous basis.
Polymyxin B sulfate is the sulfate salt of polymyxin B 1 and B 2
, which are produced by the growth of Bacillus polymyxa (Prazmowski)
Migula (Fam. Bacillaceae). It has a potency of not less than 6,000 polymyxin
B units per mg, calculated on an anhydrous basis.
Hydrocortisone, 11(beta), 17, 21-trihydroxypregn-4-ene-3,20-dione, is an anti-inflammatory
hormone.
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