A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
M-R-Vax Online, Description, Chemistry, Ingredients - Measles and Rubella Virus Vaccine Live
M-R-Vax Online, Description, Chemistry, Ingredients - Measles and Rubella Virus Vaccine Live
DESCRIPTION
M-R-VAX® II (Measles and Rubella Virus Vaccine Live), is a live virus
vaccine for immunization against measles (rubeola) and rubella (German
measles).
M-R-VAX II is a sterile lyophilized preparation of (1) ATTENUVAX* (Measles
Virus Vaccine Live), a more attenuated line of measles virus, derived
from Enders' attenuated Edmonston strain and grown in cell cultures of
chick embryo; and (2) MERUVAX* II (Rubella Virus Vaccine Live), the Wistar
RA 27/3 strain of live attenuated rubella virus grown in human diploid
cell (WI-38) culture. The vaccine viruses are the same as those used in
the manufacture of ATTENUVAX (Measles Virus Vaccine Live) and MERUVAX
II (Rubella Virus Vaccine Live). The two viruses are mixed before being
lyophilized. The product contains no preservative.
The reconstituted vaccine is for subcutaneous administration. When reconstituted
as directed, the dose for injection is 0.5 mL and contains not less than
the equivalent of 1,000 TCID 50 (tissue culture infectious
doses) of the U.S. Reference Measles Virus; and 1,000 TCID 50 of
the U.S. Reference Rubella Virus. Each dose contains approximately 25
mcg of neomycin. The product contains no preservative. Sorbitol and hydrolized
gelatin are added as stabilizers.
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