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Uvadex Online, Description, Chemistry, Ingredients - Methoxsalen

DESCRIPTION

CAUTION: READ THE UVAR PHOTOPHERESIS SYSTEM OPERATOR’S MANUAL PRIOR TO PRESCRIBING OR DISPENSING THIS MEDICATION.

UVADEX^® (Methoxsalen) STERILE SOLUTION, 20 mcg/mL

Uvadex^® (methoxsalen) Sterile Solution should be used only by physicians who have special competence in the diagnosis and treatment of cutaneous T-cell lymphoma and who have special training and experience in the UVAR^® Photopheresis System. Please consult the UVAR^® Photopheresis System Operator's Manual before using this product.

Methoxsalen is a naturally occurring photoactive substance found in the seeds of the Ammi majus (Umbelliferae) plant. It belongs to a group of compounds known as psoralens or furocoumarins. The chemical name of methoxsalen is 9-methoxy-7H-furo[3,2-g][1]-benzopyran-7-one.

Each mL of UVADEX^® (methoxsalen, 8-methoxypsoralen) Sterile Solution contains methoxsalen 20 mcg, propylene glycol 50 mg, sodium chloride 8 mg, sodium acetate 1.75 mg, ethanol 0.05 mL, glacial acetic acid 0.0012 mL, and Water for Injection q.s. to 1.0 mL.

UVADEX^® is used in combination with the UVAR^® Photopheresis System to extracorporeally treat leukocyte enriched buffy coat.

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