Alupent Side Effects, and Drug Interactions - Metaproterenol Sulfate

Alupent Side Effects, and Drug Interactions - Metaproterenol Sulfate

SIDE EFFECTS

Adverse reactions are similar to those noted with other sympathomimetic agents. The most frequent adverse reaction to Alupent® (metaproterenol sulfate USP) administered by metered-dose inhaler among 251 patients in 90-day controlled clinical trials was nervousness. This was reported in 6.8% of patients. Less frequent adverse experiences, occurring in 1-4% of patients were headache, dizziness, palpitations, gastrointestinal distress, tremor, throat irritation, nausea, vomiting, cough and asthma exacerbation. Tachycardia occurred in less than 1% of patients.

DRUG INTERACTIONS

Other beta adrenergic aerosol bronchodilators should not be used concomitantly with Alupent^® (metaproterenol sulfate USP) because they may have additive effects. Beta adrenergic agonists should be administered with caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, since the action of beta adrenergic agonists on the vascular system may be potentiated.