A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Xopenex Online, Description, Chemistry, Ingredients - Levalbuterol
Xopenex Online, Description, Chemistry, Ingredients - Levalbuterol
DESCRIPTION
Xopenex (levalbuterol HCl) Inhalation Solution is a sterile,
clear, colorless, preservative-free solution
of the hydrochloride
salt of levalbuterol, the
(R)-enantiomer of the drug
substance racemic
albuterol. Levalbuterol HCl is a relatively selective beta2-adrenergic
receptor agonist (see
CLINICAL PHARMACOLOGY). The
chemical name for levalbuterol HCl is (R)-a1-[[(1,1-
dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol hydrochloride.
The molecular weight
of levalbuterol HCl is 275.8, and its empirical formula is C13H21NO3•HCl.
It is a white to off-white,
crystalline solid,
with a melting point of
approximately 187° C and solubility
of approximately 180 mg/mL in water.
Levalbuterol HCl is the USAN
modified name for (R)-albuterol HCl in the United States.
Xopenex (levalbuterol HCl) Inhalation Solution is supplied in unit-dose
vials and requires no dilution
before administration
by nebulization. Each 3 mL unit-dose vial
contains either 0.63 mg of
levalbuterol (as 0.73 mg of levalbuterol HCl) or 1.25 mg
of levalbuterol (as 1.44 mg
of levalbuterol HCl), sodium
chloride to adjust
tonicity, and sulfuric acid
to adjust the pH to 4.0 (3.3 to 4.5).
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