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Leukeran Online, Description, Chemistry, Ingredients - Chlorambucil
DESCRIPTION
LEUKERAN (chlorambucil) was first synthesized by Everett et al. It is a bifunctional alkylating agent of the nitrogen mustard type that has been found active against selected human neoplastic diseases. Chlorambucil is known chemically as 4-[bis(2chlorethyl)amino]benzenebutanoic acid. Chlorambucil hydrolyzes in water and has a pKa of 5.8.
LEUKERAN (chlorambucil) is available in tablet
form for oral
administration. Each sugar-coated tablet
contains 2 mg chlorambucil
and the inactive ingredients acacia, corn
and wheat starch,
lactose, magnesium
stearate, pharmaceutical glaze, polysorbate 60, sucrose, and talc.
Printed with edible black
ink.
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