A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Lacrisert Online, Description, Chemistry, Ingredients - Cellulose
Lacrisert Online, Description, Chemistry, Ingredients - Cellulose
DESCRIPTION
LACRISERT (hydroxypropyl cellulose ophthalmic insert) is a sterile, translucent,
rod-shaped, water soluble, ophthalmic insert made of hydroxypropyl cellulose,
for administration into the inferior cul-de-sac of the eye.
The chemical name for hydroxypropyl cellulose is cellulose, 2-hydroxypropyl
ether. It is an ether of cellulose in which hydroxypropyl groups (-CH 2
CHOHCH 3 ) are attached to the hydroxyls present in the anhydroglucose
rings of cellulose by ether linkages.
The molecular weight is typically 1 × 10 6 .
Hydroxypropyl cellulose is an off-white, odorless, tasteless powder. It is
soluble in water below 38°C, and in many polar organic solvents such as ethanol,
propylene glycol, dioxane, methanol, isopropyl alcohol (95%), dimethyl sulfoxide,
and dimethyl formamide.
Each LACRISERT is 5 mg of hydroxypropyl cellulose. LACRISERT contains no preservatives
or other ingredients. It is about 1.27 mm in diameter by about 3.5 mm long.
LACRISERT is supplied in packages of 60 units, together with illustrated instructions
and a special applicator for removing LACRISERT from the unit dose blister and
inserting it into the eye. A spare applicator is included in each package.
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