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Triavil Pharmacology, Pharmacokinetics, Studies, Metabolism - Perphenazine and Amitriptyline

Triavil Pharmacology, Pharmacokinetics, Studies, Metabolism - Perphenazine and Amitriptyline

CLINICAL PHARMACOLOGY

ETRAFON Tablets combine the tranquilizing action of perphenazine with the antidepressant properties of amitriptyline hydrochloride. Perphenazine acts on the central nervous system, and has a greater behavioral potency than other phenothiazine derivatives whose side chains do not contain a piperazine moiety. Amitriptyline hydrochloride is a tricyclic antidepressant. While its mechanism of action in man is not known, it does not act primarily by stimulation of the central nervous system, and is not a monoamine oxidase (MAO) inhibitor.

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