A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Rimso-50 Indications, Dosage, Storage, Stability - DMSO
Rimso-50 Indications, Dosage, Storage, Stability - DMSO
INDICATIONS
AND USES
RIMSOŽ-50 (dimethyl sulfoxide) is indicated for the symptomatic relief of patients
with interstitial cystitis. RIMSOŽ-50 has not been approved as being safe and
effective for any other indication. There is no clinical evidence of effectiveness
of dimethyl sulfoxide in the treatment of bacterial infections of the urinary
tract.
DOSAGE AND ADMINISTRATION
Instillation of 50 mL of RIMSOŽ-50 (dimethyl sulfoxide) directly into the bladder
may be accomplished by catheter or aseptic syringe and allow to remain for 15
minutes. Application of an analgesic lubricant gel such as lidocaine jelly to
the urethra is suggested prior to insertion of the catheter to avoid spasm.
The medication is expelled by spontaneous voiding. It is recommended that the
treatment be repeated every two weeks until maximum symptomatic relief is obtained.
Thereafter, time intervals between therapy may be increased appropriately.
Administration of oral analgesic medication or suppositories containing belladonna
and opium prior to the instillation of RIMSOŽ-50 can reduce bladder spasm.
In patients with severe interstitial cystitis with very sensitive bladders,
the initial treatment, and possibly the second and third (depending on patient
response) should be done under anesthesia. (Saddle block has been suggested.)
HOW SUPPLIED
Bottles contain 50 mL of sterile and non-pyrogenic RIMSOŽ-50 (50% w/w dimethyl
sulfoxide aqueous solution).
Dimethyl sulfoxide is clear and colorless.
Protect from strong light
Store at room temperature (59° to 86°F) (15° to 30°C)
NDC #0433-0433-05
For additional information concerning RIMSOŽ-50, contact Edwards Lifesciences
Research Medical, Inc., Irvine, CA 92614 (800) 453-8432.
RIMSOŽ-50 is manufactured by: Ben Venue Laboratories, Inc., Bedford, OH 44146,
for Edwards Lifesciences Research Medical, Inc., Irvine, CA 92614.
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