Intal Online, Description, Chemistry, Ingredients - Cromolyn

Intal Online, Description, Chemistry, Ingredients - Cromolyn

DESCRIPTION

The active ingredient of Intal Inhaler is cromolyn sodium, usp. It is an inhaled anti-inflammatory agent for the preventive management of asthma. Cromolyn sodium is disodium 5,5’-[(2-hydroxytrimethylene)dioxylbis[4-oxo-4H-1-benzopyran-2-carboxylate]. The empirical formula is C₂₃H₁₄Na₂O₁₁;the molecular weight is 512.34.

Cromolyn sodium is a water soluble, odorless, white, hydrated crystalline powder. It is tasteless at first, but leaves a slightly bitter aftertaste.

Intal Inhaler (cromolyn sodium inhalation aerosol) is a metered dose aerosol unit for oral inhalation containing micronized cromolyn sodium, sorbitan trioleate with dichlorotetrafluoroethane and dichlorodifluoromethane as propellants. Each actuation delivers approximately 1 mg cromolyn sodium from the valve and 800 mcg cromolyn sodium through the mouthpiece to the patient. Each 8.1 g canister delivers at least 112 metered inhalations (56 doses); each 14.2 g canister delivers at least 200 metered inhalations (100 doses).