Welchol Online, Description, Chemistry, Ingredients - Colesevelam

Welchol Online, Description, Chemistry, Ingredients - Colesevelam

DESCRIPTION

WelChol™ contains colesevelam hydrochloride (hereafter referred to as colesevelam), a non-absorbed, polymeric, lipid-lowering agent intended for oral administration.

Colesevelam is a high capacity bile acid binding molecule. Colesevelam is poly(allylamine hydrochloride) cross-linked with epichlorohydrin and alkylated with 1-bromodecane and (6-bromohexyl)-trimethylammonium bromide. Colesevelam is hydrophilic, and insoluble in water.

WelChol™ is an off-white, film-coated, solid tablet containing 625 mg colesevelam. In addition, each tablet contains the following inactive ingredients: magnesium stearate, microcrystalline cellulose, and silicon dioxide. The tablets are imprinted using a water-soluble black ink.