A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Clindets Online, Description, Chemistry, Ingredients - Clindamycin
Clindets Online, Description, Chemistry, Ingredients - Clindamycin
DESCRIPTION
Clindets® (Clindamycin Phosphate Pledgets) contain clindamycin phosphate, USP
at a concentration equivalent to 10 mg clindamycin per milliliter in a vehicle
of isopropyl alcohol 52% v/v, propylene glycol and water. Each Clindets® pledget
applicator contains approximately 1 mL of Clindamycin Phosphate Topical Solution.
Clindamycin Phosphate Topical Solution has a pH range between 4.0 and 7.0.
Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic
produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent
antibiotic lincomycin. It occurs as a white to off-white, hygroscopic, crystalline
powder. It is freely soluble in water, slightly soluble in dehydrated alcohol,
very slightly soluble in acetone and practically insoluble in chloroform, benzene,
and ether. Clindamycin phosphate is odorless or practically odorless, and has
a bitter taste.
Chemically, clindamycin phosphate is C 18 H 34 ClN 2
O 8 PS. It has the following structural formula:
The chemical name for clindamycin phosphate is Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-
trans -4-propyl-L-2- pyrrolidinecarboxamido)-1-thio-L- threo -(alpha)-D-
galacto -octopyranoside 2-(dihydrogen phosphate). (MW=504.97)
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