Cetrotide Overdose, Contraindications and Information - Cetrorelix

Cetrotide Overdose, Contraindications and Information - Cetrorelix

OVERDOSE

There have been no reports of overdosage with Cetrotide^® 0.25 mg or 3 mg in humans. Single doses up to 120 mg Cetrotide^® have been well tolerated in patients treated for other indications without signs of overdosage.

Cetrotide^® (cetrorelix acetate for injection) is contraindicated under the following conditions:

1. Hypersensitivity to cetrorelix acetate, extrinsic peptide hormones or mannitol.

2. Known hypersensitivity to GnRH or any other GnRH analogs.

3. Known or suspected pregnancy, and lactation (see PRECAUTIONS).

4. Severe renal impairment