A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Ancef Side Effects, and Drug Interactions - Cefazolin
Ancef Side Effects, and Drug Interactions - Cefazolin
SIDE EFFECTS
The following reactions have been reported:
Gastrointestinal
Diarrhea, oral candidiasis (oral thrush), vomiting, nausea,
stomach cramps, anorexia, and pseudomembranous colitis. Onset of pseudomembranous
colitis symptoms may occur during or after antibiotic treatment (see WARNINGS).
Nausea and vomiting have been reported rarely.
Allergic
Anaphylaxis, eosinophilia, itching, drug fever, skin rash,
Stevens-Johnson syndrome.
Hematologic
Neutropenia, leukopenia, thrombocytopenia, thrombocythemia.
Hepatic
Transient rise in SGOT, SGPT, and alkaline phosphatase levels
has been observed. As with other cephalosporins, reports of hepatitis have been
received.
Renal
As with other cephalosporins, reports of increased BUN and
creatinine levels, as well as renal failure, have been received.
Local Reactions
Rare instances of phlebitis have been reported at site of injection.
Pain at the site of injection after intramuscular administration has occurred
infrequently. Some induration has occurred.
Other Reactions
Genital and anal pruritus (including vulvar pruritus, genital
moniliasis, and vaginitis).
DRUG INTERACTIONS
Probenecid may decrease renal tubular secretion of cephalosporins
when used concurrently, resulting in increased and more prolonged cephalosporin
blood levels.
Drug/Laboratory Test Interactions
A false positive reaction for glucose in the urine may occur
with Benedict’s solution, Fehling’s solution or with CLINITEST®
tablets, but not with enzyme-based tests such as CLINISTIX®.
Positive direct and indirect antiglobulin (Coombs) tests have
occurred; these may also occur in neonates whose mothers received cephalosporins
before delivery.
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