A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Mandol Side Effects, and Drug Interactions - Cefamandole
Mandol Side Effects, and Drug Interactions - Cefamandole
SIDE EFFECTS
Gastrointestinal Symptoms of pseudomembranous colitis may appear
either during or after antibiotic treatment. Nausea and vomiting have been reported
rarely. As with some penicillins and some other cephalosporins, transient hepatitis
and cholestatic jaundice have been reported rarely.
Hypersensitivity Anaphylaxis, maculopapular rash, urticaria,
eosinophilia, and drug fever have been reported. These reactions are more likely
to occur in patients with a history of allergy, particularly to penicillin.
Blood Thrombocytopenia has been reported rarely. Neutropenia
has been reported, especially in long courses of treatment. Some individuals
have developed positive direct Coombs' tests during treatment with the cephalosporin
antibiotics.
Liver Transient rise in SGOT, SGPT, and alkaline phosphatase
levels has been noted.
Kidney Decreased creatinine clearance has been reported in patients
with prior renal impairment. As with some other cephalosporins, transitory elevations
of BUN have occasionally been observed with Mandol; their frequency increases
in patients over 50 years of age. In some of these cases, there was also a mild
increase in serum creatinine.
Local Reactions Pain on intramuscular injection is infrequent.
Thrombophlebitis occurs rarely.
DRUG INTERACTIONS
No Information Provided
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