Gynazole Online, Description, Chemistry, Ingredients - Butoconazole

Gynazole Online, Description, Chemistry, Ingredients - Butoconazole

Gynazole·1®
(butoconazole nitrate) Vaginal Cream, 2%
In one prefilled disposable applicator

Rx Only

GYNAZOLE·1™ (butoconazole nitrate) vaginal cream, 2% contains butoconazole nitrate 2%, an imidazole derivative with antifungal activity. Its chemical name is (±)-1-[4-(p-chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl] imidazole mononitrate, and it has the following chemical structure:

Butoconazole nitrate is a white to off-white crystalline powder with a molecular weight of 474.79. It is sparingly soluble in methanol; slightly soluble in chloroform, methylene chloride, acetone, and ethanol; very slightly soluble in ethyl acetate; and practically insoluble in water. It melts at about 159°C with decomposition.

GYNAZOLE·1™ contains 2% butoconazole nitrate in a cream of edetate disodium, glyceryl monoisostearate, methylparaben, mineral oil, polyglyceryl-3 oleate, propylene glycol, propylparaben, colloidal silicon dioxide, sorbitol solution, purified water, and microcrystalline wax.