A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Dimetane Side Effects, and Drug Interactions - Brompheniramine, Phenylpropanolamine, and Codeine
Dimetane Side Effects, and Drug Interactions - Brompheniramine, Phenylpropanolamine, and Codeine
SIDE EFFECTS
The most frequent adverse reactions to this product
are: sedation; dryness of mouth,
nose and throat; thickening of
bronchial secretions; dizziness.
Other adverse reactions may include:
Dermatologic: Urticaria, drug
rash, photosensitivity,
pruritus.
Cardiovascular System: Hypotension, hypertension,
cardiac arrhythmias.
CNS: Disturbed coordination, tremor,
irritability, insomnia, visual disturbances, weakness, nervousness,
convulsions, headache,
euphoria and dysphoria.
G.U. System: Urinary frequency, difficult urination.
G.I. System: Epigastric discomfort, anorexia,
nausea, vomiting, diarrhea,
constipation.
Respiratory System: Tightness of chest
and wheezing, shortness
of breath. At higher doses, codeine
has most of the disadvantages of morphine including respiratory
depression.
Hematologic System: Hemolytic anemia,
thrombocytopenia,
agranulocytosis.
DRUG ABUSE AND DEPENDENCE
Codeine can produce a drug dependence
of the morphine type, and
therefore has the potential
for being abused. Psychic dependence,
physical dependence, physical
dependence and tolerance
may develop upon repeated administration of this drug
and it should be prescribed and administered with the same degree of caution
appropriate to the use
of other oral narcotic
medications.
The product is subject
to the Federal Controlled Substances Act (Schedule V).
DRUG INTERACTIONS
Antihistamines have additive
effects with alcohol and other
CNS depressants (hypnotics, sedatives,
tranquilizers, antianxiety agents, etc.). MAO
inhibitors prolong and intensify the anticholinergic
(drying) effects of antihistamines. MAO inhibitors may enhance the effect
of phenylpropanolamine. Sympathomimetics may reduce
the effects of antihypertensive
drugs.
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