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Celestone Side Effects, and Drug Interactions - Betamethasone

Celestone Side Effects, and Drug Interactions - Betamethasone

SIDE EFFECTS

Fluid and electrolyte disturbances:   sodium retention, fluid retention, congestive heart failure in susceptible patients, potassium loss, hypokalemic alkalosis, hypertension.

Musculoskeletal:   muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, aseptic necrosis of femoral and humeral heads, pathologic fracture of long bones.

Gastrointestinal:   peptic ulcer with possible perforation and hemorrhage, pancreatitis, abdominal distention, ulcerative esophagitis, hiccups.

Dermatologic:   impaired wound healing; thin, fragile skin; petechiae and ecchymoses; facial erythema; increased sweating; may suppress reactions to skin tests.

Neurological:   convulsions, increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment, vertigo, headache.

Endocrine:   menstrual irregularities; development of cushingoid state; suppression of growth in children; secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery, or illness; decreased carbohydrate tolerance; manifestations of latent diabetes mellitus; increased requirements of insulin or oral hypoglycemic agents in diabetics.

Ophthalmic:   posterior subcapsular cataracts, increased intraocular pressure, glaucoma, exophthalmos.

Metabolic:   negative nitrogen balance due to protein catabolism.

Other:   anaphylactoid or hypersensitivity and hypotensive or shock-like reactions.

 

DRUG INTERACTIONS

No Information Provided.

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