Regranex Side Effects, and Drug Interactions - Becaplermin

Regranex Side Effects, and Drug Interactions - Becaplermin

SIDE EFFECTS

Patients receiving REGRANEX Gel, placebo gel, and good ulcer care alone had a similar incidence of ulcer-related adverse events such as infection, cellulitis, or osteomyelitis. However, erythematous rashes occurred in 2% of patients treated with REGRANEX Gel and placebo, and none in patients receiving good ulcer care alone. The incidence of cardiovascular, respiratory, musculoskeletal and central and peripheral nervous system disorders was not different across all treatment groups. Mortality rates were also similar across all treatment groups. Patients treated with REGRANEX Gel did not develop neutralizing antibodies against becaplermin.

DRUG INTERACTIONS

It is not known if REGRANEX Gel interacts with other topical medications applied to the ulcer site. The use of REGRANEX Gel with other topical drugs has not been studied.