Colazal Online, Description, Chemistry, Ingredients - Balsalazide

Colazal Online, Description, Chemistry, Ingredients - Balsalazide

COLAZAL®
(balsalazide disodium) Capsules
(kôl a zal)

Each COLAZAL capsule contains 750 mg of balsalazide disodium, a prodrug that is enzymatically cleaved in the colon to produce mesalamine (5-aminosalicylic acid), an anti inflammatory drug. Each daily dose of COLAZAL (6.75 grams) is equivalent to 2.4 grams of mesalamine. Balsalazide disodium has the chemical name (E)-5-[[-4-[[(2-carboxyethyl) amino]carbonyl] phenyl]azo] -2-hydroxybenzoic acid, disodium salt, dihydrate. Its structual formula is:

Molecular Weight: 437.32

Molecular Formula: C ₁₇ H ₁₃ N ₃ O ₆ Na ₂ • 2H ₂ O

Balsalazide disodium is a stable, odorless orange to yellow microcrystalline powder. It is freely soluble in water and isotonic saline, sparingly soluble in methanol and ethanol, and practically insoluble in all other organic solvents.

Inactive Ingredients:   Each hard gelatin capsule contains colloidal silicon dioxide and magnesium stearate. The sodium content of each capsule is approximately 86 mg.