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Bactrim Online, Description, Chemistry, Ingredients - Trimethoprim and Sulfamethoxazole
DESCRIPTION
Bactrim (trimethoprim and sulfamethoxazole) IV Infusion, a sterile solution for intravenous infusion only, is a synthetic antibacterial combination product. Each 5 mL contains 80 mg trimethoprim (16 mg/mL) and 400 mg sulfamethoxazole (80 mg/mL) compounded with 40% propylene glycol, 10% ethyl alcohol and 0.3% diethanolamine; 1% benzyl alcohol and 0.1% sodium metabisulfite added as preservatives, water for injection, and pH adjusted to approximately 10 with sodium hydroxide.
Trimethoprim is 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine. It is a white to light yellow, odorless, bitter compound with a molecular weight of 290.3.
Sulfamethoxazole is N 1 -(5-methyl-3-isoxazolyl)sulfanilamide. It is an almost white, odorless, tasteless compound with a molecular weight of 253.28.
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