Sectral Online, Description, Chemistry, Ingredients - Acebutolol

Sectral Online, Description, Chemistry, Ingredients - Acebutolol

DESCRIPTION

Acebutolol hydrochloride is a selective, hydrophilic beta-adrenoreceptor blocking agent with mild intrinsic sympathomimetic activity for use in treating patients with hypertension and ventricular arrhythmias. It is marketed in capsule form for oral administration. Acebutolol hydrochloride capsules are available in two strengths which contain 200 or 400 mg of acebutolol as the hydrochloride salt. The inactive ingredients are gelatin, methylparaben, povidone, pregelatinized starch, propylparaben, silicon dioxide, sodium lauryl sulfate, stearic acid, titanium dioxide, FD&C Blue #1, FD&C Red #40, D&C Yellow #10, D&C Red #28, FD&C Blue #2, and black iron oxide.

The molecular formula is C₁₈H₂₈N₂O₄•HCl and its molecular weight is M.W. 372.9.

Acebutolol HCl is a white or slightly off-white powder freely soluble in water, and less soluble in alcohol. Chemically it is defined as the hydrochloride salt of Butanamide, N-[3-acetyl-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-phenyl]-,(+/-)- or(+/-) -3’-Acetyl-4[2- hydroxy-3-(isopropylamino) propoxy] butyranilide.