A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Septra Online, Description, Chemistry, Ingredients - Trimethoprim and Sulfamethoxazole
Septra Online, Description, Chemistry, Ingredients - Trimethoprim and Sulfamethoxazole
SEPTRA® Tablets
SEPTRA® DS (Double Strength) Tablets
SEPTRA® Suspension
SEPTRA® Grape Suspension
(trimethoprim and sulfamethoxazole)
DESCRIPTION
SEPTRA (trimethoprim and sulfamethoxazole) is a synthetic antibacterial
combination product. Each SEPTRA Tablet contains 80 mg trimethoprim and 400
mg sulfamethoxazole and the inactive ingredients docusate sodium (0.4 mg per
tablet), FD&C Red No. 40, magnesium stearate, povidone, and sodium starch
glycolate.
Each SEPTRA DS (double strength) Tablet contains 160 mg trimetho-prim and 800 mg sulfamethoxazole and the inactive ingredients docusate sodium (0.8 mg per tablet), FD&C Red No. 40, magnesium stearate, povidone, and sodium starch glycolate.
Each teaspoonful (5 mL) of SEPTRA Suspension contains 40 mg trimethoprim and 200 mg sulfamethoxazole and the inactive ingredients alcohol 0.26%, methylparaben 0.1% and sodium benzoate 0.1% (added as preservatives), carboxymethylcellulose sodium, citric acid, FD&C Red No.40 and Yellow No.6, flavor, glycerin, microcrystalline cellulose, polysorbate 80, saccharin sodium, and sorbitol. Each teaspoonful (5 mL) of SEPTRA Grape Suspension contains 40 mg trimethoprim and 200 mg sulfamethoxazole and the inactive ingredients alcohol 0.26%, methylparaben 0.1%, and sodium benzoate 0.1% (added as preservatives), carboxymethylcellulose sodium, citric acid, FD&C Red No. 40 and Blue No. 1, flavor, glycerin, microcrystalline cellulose, polysorbate 80, saccharin sodium, and sorbitol. Both tablet and suspension forms are for oral administration.
Trimethoprim is 5-[(3, 4, 5-trimethoxyphenyl)methyl]-2, 4-pyrimidinedi-amine. It is a white to light yellow, odorless, bitter compound with a molecular weight of 290.32, and the molecular formula C14H18N4O3. The structural formula is:
Sulfamethoxazole is 4-amino-N-(5-methyl-3-isoxazolyl)benzenesulfon-amide. It is an almost white, odorless, tasteless compound with a molecular weight
of 253.28, and the molecular formula C10H11N3O3S. The structural formula is:
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