A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Nasacort Online, Description, Chemistry, Ingredients - Triamcinolone Acetonide
Nasacort Online, Description, Chemistry, Ingredients - Triamcinolone Acetonide
NASACORT® HFA
[na’ za-cort]
(triamcinolone acetonide)
Nasal Aerosol
For Intranasal Use Only
Shake Well Before Using
DESCRIPTION
Triamcinolone acetonide, USP, the active ingredient in Nasacort®
HFA Nasal Aerosol, is a glucocorticosteroid with a molecular weight of 434.5,
the chemical designation 9-Fluoro-11ß,16a,17,
21-tetrahydroxypregna-1, 4-diene-3, 20-dione cyclic 16,17-acetal with acetone
(C24H31FO6), and the following chemical structure:
Triamcinolone acetonide is a white to cream-colored crystalline
powder, practically insoluble in water, very soluble in dehydrated alcohol,
chloroform, and methyl alcohol.
Nasacort HFA Nasal Aerosol is a metered-dose aerosol unit containing
a microcrystalline suspension of triamcinolone acetonide in tetrafluo-roethane
(HFA-134a) and dehydrated alcohol USP 0.7% w/w. Each canister contains 15 mg
of triamcinolone acetonide.
The canister must be primed with 3 actuations prior to the
first use or after a period of non-use (3 days). After priming, each actuation
meters 100 mcg of triamcinolone acetonide in 65 mg of suspension from the valve
and delivers 55 mcg of triamcinolone acetonide from the nasal actuator to the
patient. If the product is not used for more than 3 days, it should be re-primed
with 3 actuations.
Each 9.3 g canister of Nasacort HFA Nasal Aerosol provides
100 metered sprays. After 100 metered sprays, this amount of medication delivered
per actuation may not be consistent and the unit should be discarded. Patients
are provided with a check-off card to track usage as part of the PATIENT INFORMATION
For use tear-off sheet.
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