Trelstar Overdose, Contraindications and Information - Triptorelin pamoate

Trelstar Overdose, Contraindications and Information - Triptorelin pamoate

OVERDOSE

There is no experience of overdosage in clinical trials. In single dose toxicity studies in mice and rats, the subcutaneous LD50 of trip-torelin was 400 mg/kg in mice and 250 mg/kg in rats, approximately 7000 and 4000 times, respectively, the usual human dose. If over-dosage occurs however, therapy should be discontinued immediately and the appropriate supportive and symptomatic treatment administered.

TRELSTAR^TM LA is contraindicated in individuals with a known hypersensitivity to triptorelin or any other component of the product, other LHRH agonists or LHRH.

TRELSTAR^TM LA is contraindicated in women who are or may become pregnant while receiving the drug. TRELSTAR^TM LA may cause fetal harm when administered to a pregnant woman.