Tetanus Toxoid Online, Description, Chemistry, Ingredients - Tetanus Toxoid USP

Tetanus Toxoid Online, Description, Chemistry, Ingredients - Tetanus Toxoid USP

DESCRIPTION

Tetanus Toxoid USP, for intramuscular or subcutaneous use, is a sterile solution of toxoid in isotonic sodium chloride solution. The vaccine is clear or slightly turbid in appearance.

Clostridium tetani culture is grown in a peptone-based medium and detoxified with formaldehyde. The detoxified material is then purified by serial ammonium sulfate fractionation, followed by sterile filtration. The toxoid is then diluted with physiological saline solution (0.85%) and thimerosal (a mercury derivative) is added to a final concentration of 1:10,000.

Each 0.5 mL dose is formulated to contain 4 Lf (flocculation units) of tetanus toxoid and passes the guinea pig potency test. The residual formaldehyde content, by assay, is less than 0.02%.