Imitrex Online, Description, Chemistry, Ingredients - Sumatriptan Succinate (intranasal)

Imitrex Online, Description, Chemistry, Ingredients - Sumatriptan Succinate (intranasal)

DESCRIPTION

Sumatriptan is a selective 5-hydroxytryptamine₁ receptor subtype agonist. Sumatriptan is chemically designated as 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide.

The empirical formula is C₁₄H₂₁N₃O₂S, representing a molecular weight of 295.4. Sumatriptan is a white to off-white powder that is readily soluble in water and saline. Each Imitrex nasal spray contains 5 or 20 mg of sumatriptan in a 100-mcl unit dose aqueous buffered solution containing monobasic potassium phosphate, anhydrous dibasic sodium phosphate, sulfuric acid, sodium hydroxide, and purified water. The pH of the solution is approximately 5.5. The osmolality of the solution is 372 or 742 mOsmol for the 5- and 20-mg Imitrex nasal spray, respectively.