A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Actonel Online, Description, Chemistry, Ingredients - Risedronate
Actonel Online, Description, Chemistry, Ingredients - Risedronate
DESCRIPTION
ACTONEL (risedronate sodium tablets) is a pyridinyl bisphosphonate
that inhibits osteoclast-mediated bone resorption and modulates bone metabolism.
Each ACTONEL tablet for oral administration contains the equivalent of 5, 30,
or 35 mg of anhydrous risedronate sodium in the form of the hemi-pentahydrate
with small amounts of monohydrate. The empirical formula for risedronate sodium
hemi-pentahydrate is C7H10NO7P2Na
•2.5 H2O. The chemical name of risedronate sodium is [1-hydroxy-2-(3-pyridinyl)ethylidene]bis[phosphonic
acid] monosodium salt. The chemical structure of risedronate sodium hemi-pentahydrate
is the following:
Molecular Weight:
Anhydrous: 305.10
Hemi-pentahydrate: 350.13
Risedronate sodium is a fine, white to off-white, odorless,
crystalline powder. It is soluble in water and in aqueous solutions, and essentially
insoluble in common organic solvents.
Inactive Ingredients
Crospovidone, ferric oxide red (35-mg tablets only), ferric
oxide yellow (5 and 35-mg tablets only), hydroxypropyl cellulose, hydroxypropyl
methylcellulose, lactose monohydrate, magnesium stearate, microcrystalline cellulose,
polyethylene glycol, silicon dioxide, titanium dioxide.
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