Rescriptor Overdose, Contraindications and Information - Delavirdine mesylate

Rescriptor Overdose, Contraindications and Information - Delavirdine mesylate

OVERDOSE

No reports of overdose with RESCRIPTOR Tablets are available in humans. Several patients have received up to 850 mg tid for up to 6 months with no serious drug-related medical events.

Management of Overdosage: Treatment of overdosage with RESCRIPTOR should consist of general supportive measures, including monitoring of vital signs and observation of the patient’s clinical status. There is no specific antidote for overdosage with RESCRIPTOR. If indicated, elimination of unabsorbed drug should be achieved by emesis or gastric lavage. Since delavirdine is extensively metabolized by the liver and is highly protein bound, dialysis is unlikely to result in significant removal of the drug.

RESCRIPTOR Tablets are contraindicated in patients with previously demonstrated clinically significant hypersensitivity to any of the components of the formulation.