Remodulin Online, Description, Chemistry, Ingredients - Treprostinil sodium

Remodulin Online, Description, Chemistry, Ingredients - Treprostinil sodium

REMODULIN^TM (treprostinil sodium) Injection

Remodulin (treprostinil sodium) Injection is a sterile sodium salt formulated for subcutaneous administration. Remodulin is supplied in 20 mL multi-use vials in four strengths, containing 1.0 mg/mL, 2.5 mg/mL, 5.0 mg/mL or 10.0 mg/mL of treprostinil. Each mL also contains 5.3 mg sodium chloride (except for the 10.0 mg/mL strength which contains 4.0 mg sodium chloride), 3.0 mg metacresol, 6.3 mg sodium citrate, and water for injection. Sodium hydroxide and hydrochloric acid may be added to adjust pH between 6.0 and 7.2.

Treprostinil is chemically stable at room temperature and neutral pH.

Treprostinil sodium is (1R,2R,3aS,9aS)-[[2,3,3a,4,9,9a-Hexahydro-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]inden-5-yl]oxy]acetic acid monosodium salt. Treprostinil sodium has a molecular weight of 412.49 and a molecular formula of C₂₃H₃₃NaO₅.