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Quadramet Overdose, Contraindications and Information - Samarium SM 153 Lexidronam

Quadramet Overdose, Contraindications and Information - Samarium SM 153 Lexidronam

OVERDOSE

Overdosage with Quadramet has not been reported. An antidote for Quadramet overdosage is not known. The anticipated complications of overdosage would likely be secondary to bone marrow suppression from the radioactivity of 153Sm, or secondary to hypocalcemia and cardiac arrhythmias related to the EDTMP.

CONTRAINDICATIONS

Quadramet is contraindicated in patients who have known hypersensitivity to EDTMP or similar phosphonate compounds.

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