A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Prilosec Online, Description, Chemistry, Ingredients - Omeprazole
Prilosec Online, Description, Chemistry, Ingredients - Omeprazole
DESCRIPTION
The active ingredient
in Prilosec Delayed-Release Capsules is a substituted benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole,
a compound that inhibits
gastric acid
secretion. Its empirical
formula is C17H19N3O3S, with a
molecular weight of 345.42. The structural formula is:
Omeprazole is a white to off-white
crystalline powder
which melts with decomposition at about 155°C. It is a weak
base, freely soluble in ethanol
and methanol, and slightly soluble
in acetone and isopropanol
and very slightly soluble
in water. The stability of omeprazole
is a function of pH; it is rapidly degraded in acid
media, but has acceptable stability under alkaline
conditions.
Prilosec is supplied as delayed-release capsules for oral
administration. Each delayed-release capsule
contains either 10 mg or 20 mg of omeprazole in the form
of enteric-coated granules
with the following inactive ingredients: cellulose, disodium hydrogen
phosphate, hydroxypropyl cellulose, hydroxypropyl methylcellulose, lactose,
mannitol, sodium lauryl sulfate
and other ingredients. The capsule
shells have the following inactive ingredients: gelatin-NF, FD&C blue
#1, FD&C red #40, D&C
red #28, titanium
dioxide, synthetic black iron
oxide, isopropanol, butyl alcohol, FD&C blue
#2, D&C red #7 calcium
lake, and, in addition, the 10 mg capsule
shell also contains D&C yellow
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