Olux Online, Description, Chemistry, Ingredients - Clobetasol propionate

Olux Online, Description, Chemistry, Ingredients - Clobetasol propionate

OLUXäFoam, 0.05%

(clobetasol propionate)

For Dermatologic Use Only Not for Ophthalmic Use

OLUX Foam contains clobetasol propionate, USP, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.

Clobetasol propionate is (11,16)-21-chloro-9-fluoro-11-hydroxy-16-methyl-17 (1-oxopropoxy)-pregna-1,4-diene-3,20-dione, with the empirical formula C₂₅H₃₂CIFO₅, a molecular weight of 466.98 (CAS Registry Number 25122-46-7). The following is the chemical structure:

Clobetasol propionate is a white or almost white, odorless, crystalline powder and is insoluble in water.

Each gram of OLUX Foam contains 0.5 mg clobetasol propionate, USP, in a thermolabile foam, which consists of ethanol (60%), purified water, propylene glycol, cetyl alcohol, stearyl alcohol, polysorbate 60, citric acid, and potassium citrate. OLUX Foam is dispensed from an aluminum can pressurized with a hydrocarbon propellant (propane/butane).