A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Demerol Indications, Dosage, Storage, Stability - Meperidine
Demerol Indications, Dosage, Storage, Stability - Meperidine
INDICATIONS
- For the relief of
moderate to severe pain
(parenteral and oral
forms)
- For preoperative medication
(parenteral form only)
- For support of anesthesia
(parenteral form only)
- For obstetrical analgesia
(parenteral form only)
DOSAGE AND ADMINISTRATION
For Relief of Pain
Dosage should be adjusted according to the severity of the pain
and the response of
the patient. While subcutaneous administration is suitable for occasional
use, intramuscular
administration is preferred when repeated doses are required. If
intravenous administration
is required, dosage should
be decreased and the injection
made very slowly, preferably utilizing a diluted solution. Meperidine
is less effective orally than on parenteral
administration. The dose
of meperidine should be proportionately reduced (usually by 25 to
50 percent) when administered concomitantly with phenothiazines
and many other tranquilizers since they potentiate
the action of meperidine.
Adults: The usual dosage is 50 mg
to 150 mg intramuscularly,
subcutaneously, or orally, every 3 or 4 hours as necessary.
Children: The usual dosage
is 0.5 mg/lb to 0.8 mg/lb intramuscularly, subcutaneously, or orally
up to the adult dose,
every 3 or 4 hours as necessary.
Each dose of the syrup
should be taken in one-half glass
of water, since if taken undiluted, it may exert a slight topical
anesthetic effect
on mucous membranes.
For Preoperative Medication
Adults: The usual dosage is 50 mg
to 100 mg intramuscularly
or subcutaneously, 30 to 90 minutes before the beginning of anesthesia.
Children: The usual dosage
is 0.5 mg/lb to 1 mg/lb intramuscularly or subcutaneously up to
the adults does, 30 to 90 minutes before the beginning of anesthesia.
For Support of Anesthesia
Repeated slow intravenous
injections of fractional dosages (e.g., 10 mg/ml) or continuous
intravenous infusion of a more dilute solution
(e.g., 1 mg/ml) should be used. The dose
should be titrated to the needs of the patient
and will depend on the
premedication
and type of anesthesia
being employed, the characteristics of the particular patient,
and the nature and duration
of the operative procedure.
For Obstetrical Analgesia
The usual dosage is
50 mg to 100 mg intramuscularly
or subcutaneously when pain
becomes regular, and may be repeated at 1- to 3-hour intervals.
HOW SUPPLIED
No information provided.
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