A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Indocin Online, Description, Chemistry, Ingredients - Indomethacin
Indocin Online, Description, Chemistry, Ingredients - Indomethacin
DESCRIPTION
INDOCIN* (Indomethacin) cannot be considered a simple analgesic and should not be used in
conditions other than those recommended under INDICATIONS.
INDOCIN is supplied in three dosage forms. Capsules INDOCIN for oral administration contain either
25 mg or 50 mg of indomethacin and the following inactive ingredients: colloidal silicon dioxide, FD&C
Blue 1, FD&C Red 3, gelatin, lactose, lecithin, magnesium stearate, and titanium dioxide. Suspension
INDOCIN for oral use contains 25 mg of indomethacin per 5 mL, alcohol 1%, and sorbic acid 0.1% added
as a preservative and the following inactive ingredients: antifoam AF emulsion, flavors, purified water,
sodium hydroxide or hydrochloric acid to adjust pH, sorbitol solution, tragacanth. Suppositories INDOCIN
for rectal use contain 50 mg of indomethacin and the following inactive ingredients: butylated
hydroxyanisole, butylated hydroxytoluene, edetic acid, glycerin, polyethylene glycol 3350, polyethylene
glycol 8000 and sodium chloride. Indomethacin is a non-steroidal anti-inflammatory indole derivative
designated chemically as 1-(4-chlorobenzoyl)-5-methoxy -2-methyl-1H-indole-3-acetic acid. Indomethacin
is practically insoluble in water and sparingly soluble in alcohol. It has a pKa of 4.5 and is stable in neutral
or slightly acidic media and decomposes in strong alkali. The suspension has a pH of 4.0-5.0. The
structural formula is:
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