Robitussin Ac Pharmacology, Pharmacokinetics, Studies, Metabolism - Guaifenesin and Codeine

Robitussin Ac Pharmacology, Pharmacokinetics, Studies, Metabolism - Guaifenesin and Codeine

CLINICAL PHARMACOLOGY

This syrup preparation combines the expectorant, guaifenesin, with the cough suppressant, codeine. Guaifenesin enhances the output of lower respiratory tract fluid. The enhanced flow of less viscid secretions promotes and facilitates the removal of mucus. Codeine is a centrally acting agent which elevates the threshold for cough. As a result, dry, unproductive coughs become more productive and less frequent.