Gabitril Online, Description, Chemistry, Ingredients - Tiagabine Hcl

Gabitril Online, Description, Chemistry, Ingredients - Tiagabine Hcl

GABITRIL®

GABITRIL (tiagabine HCl) is an antiepilepsy drug available as 2 mg, 4 mg, 12 mg, and 16 mg tablets for oral administration. Its chemical name is (-)-(R)-1-[4,4-Bis(3- methyl-2-thienyl)-3-butenyl]nipecotic acid hydrochloride, its molecular formula is C₂₀H₂₅NO₂S₂ HCl, and its molecular weight is 412.0. Tiagabine HCl is a white to off-white, odorless, crystalline powder. It is insoluble in heptane, sparingly soluble in water, and soluble in aqueous base. The structural formula is:

Inactive Ingredients

GABITRIL tablets contain the following inactive ingredients: Ascorbic acid, colloidal silicon dioxide, crospovidone, hydrogenated vegetable oil wax, hydroxypropyl cellulose, hypromellose, lactose, magnesium stearate, microcrystalline cellulose, pregelatinized starch, stearic acid, and titanium dioxide.

In addition, individual tablets contain:

2 mg tablets: FD&C Yellow No. 6.

4 mg tablets: D&C Yellow No. 10.

12 mg tablets: D&C Yellow No. 10 and FD&C Blue No. 1.

16 mg tablets: FD&C Blue No. 2.