A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Eloxatin Online, Description, Chemistry, Ingredients - Oxaliplatin
Eloxatin Online, Description, Chemistry, Ingredients - Oxaliplatin
ELOXATIN
Oxaliplatin for injection
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WARNING
ELOXATIN (oxaliplatin for injection) should be administered under the
supervision of a qualified physician experienced in the use of cancer
chemotherapeutic agents. Appropriate management of therapy and complications
is possible only when adequate diagnostic and treatment facilities are
readily available.
Anaphylactic-like reactions to ELOXATIN have been reported, and may occur
within minutes of ELOXATIN administration. Epinephrine, corticosteroids,
and antihistamines have been employed to alleviate symptoms. (See WARNINGS
and ADVERSE REACTIONS.)
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ELOXATIN™ (oxaliplatin for injection) is an antineoplastic agent with the molecular
formula C8H14N2O4Pt and the chemical
name of cis-[(1R,2R)-1,2-cyclohexanediamine-N,N’]
[oxalato(2-)-O,O’] platinum. Oxaliplatin is an organoplatinum
complex in which the platinum atom is complexed with
1,2-diaminocyclohexane (DACH) and with an oxalate ligand as a leaving
group.
The molecular weight is 397.3. Oxaliplatin is slightly soluble in
water at 6 mg/mL, very slightly soluble in methanol, and practically insoluble
in ethanol and acetone.
ELOXATIN is supplied in vials containing 50 mg or 100 mg of oxaliplatin as
a sterile, preservative-free lyophilized powder for reconstitution. Lactose
monohydrate is present as an inactive ingredient at 450 mg and 900 mg in the
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