A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Benadryl Indications, Dosage, Storage, Stability - Diphenhydramine
Benadryl Indications, Dosage, Storage, Stability - Diphenhydramine
INDICATIONS
Capsules and Elixir
Diphenhydramine HCl in the oral
form is effective for the
following indications:
Antihistaminic: For allergic
conjunctivitis
due to foods; mild, uncomplicated allergic
skin manifestations of
urticaria and angioedema;
amelioration of allergic
reactions to blood or
plasma; dermatographism; as therapy
for anaphylactic reactions adjunctive to epinephrine and
other standard measures
after the acute manifestations
have been controlled.
Motion sickness: For active and prophylactic
treatment of motion
sickness.
Antiparkinsonism: For parkinsonism
(including drug-induced) in the elderly unable to tolerate more
potent agents; mild cases
of parkinsonism (including drug-induced) in other age
groups; in other cases of parkinsonism (including drug-induced)
in combination with centrally acting anticholinergic agents.
Injection
Diphenhydramine HCl in the injectable
form should only be used
when the oral forms are
impractical.
DOSAGE AND ADMINISTRATION
DOSAGE SHOULD BE INDIVIDUALIZED ACCORDING TO
THE NEEDS AND THE RESPONSE OF THE PATIENT.
Capsules
A single oral dose
of diphenhydramine hydrochloride
is quickly absorbed with maximum
activity occurring
in approximately one hour. The duration of activity
following an average
dose of diphenhydramine
HCl is from four to six hours.
Adults: 25 to 50 mg
three or four times daily.
Children (over 20 lb): 12.5 to 25 mg
three to four times daily. Maximum daily dosage
not to exceed 300 mg. For physicians who w.s.
to calculate the dose on
the basis of body
weight or surface
area, the recommended dosage is 5 mg/kg/24 hours or 150 mg/m2/24
hours.
The basis for determining
the most effective dosage
regimen will
be the response of
the patient to medication
and the condition
under treatment.
In motion sickness,
full dosage is recommended
for prophylactic
use, the first dose to
be given 30 minutes before exposure
to motion and similar
doses before meals and upon retiring for the duration
of exposure.
Elixir
A single oral dose
of diphenhydramine hydrochloride
is quickly absorbed with maximum
activity occurring
in approximately one hour. The duration of activity
following an average
dose of diphenhydramine
HCl is from four to six hours.
Children (over 20 lb): One to two teaspoonfuls three to
four times daily. Maximum daily dosage
not to exceed 300 mg.
For physicians who w.s.
to calculate the dose on
the basis of body
weight or surface area,
the recommended dosage
is 5 mg/kg/24 hours or 150 mg/m2/24 hours.
Adults: Two to four teaspoonfuls three to four times daily.
The basis for determining the most effective dosage
regimen will
be the response of the patient
to medication and
the condition under
treatment.
In motion sickness,
full dosage is recommended
for prophylactic
use, the first dose to
be given 30 minutes before exposure
to motion and similar
doses before meals and upon retiring for the duration
of exposure.
Injection
Parenteral drug products
should be inspected visually for particulate matter and discoloration
prior to administration, whenever solution
and container permit.
Children: 5 mg/kg/24 hr
or 150 mg/m2/24 hr. Maximum daily dosage
is 300 mg. Divide into four doses, administered intravenously or
deeply intramuscularly.
Adults: 10 to 50 mg
intravenously or deep intramuscularly,
100 mg if required; maximum
daily dosage is 400 mg.
Store at controlled room
temperature 15-30°C
(59-86°F). Protect from moisture, freezing, and light.
HOW SUPPLIED
No information provided.
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