A1,
A2,
B,
C1,
C2,
D,
E,
F,
G-H,
I-K,
L,
M,
N,
O,
P1,
P2,
Q-R,
S,
T,
U-V,
W-Z
Bentyl Side Effects, and Drug Interactions - Dicyclomine
Bentyl Side Effects, and Drug Interactions - Dicyclomine
SIDE EFFECTS
Controlled clinical
trials have provided frequency
information for reported adverse effects of dicyclomine hydrochloride
listed in a decreasing order of frequency. (See CLINICAL
PHARMACOLOGY)
Not all of the following adverse reactions have been reported with
dicyclomine hydrochloride. Adverse reactions are included here that
have been reported for pharmacologically similar drugs with anticholinergic/antispasmodic
action.
Gastrointestinal: dry mouth
nausea, vomiting,
constipation. bloated feeling, abdominal
pain, taste
loss, anorexia.
Central Nervous System: dizziness,
lightheadedness, tingling, headache, drowsiness,
weakness, nervousness, numbness, mental
confusion and/or excitement (especially in elderly persons), dyskinesia,
lethargy, syncope, speech
disturbance, insomnia.
Ophthalmologic: blurred vision. diplopia,
mydriasis, cycloplegia,
increased ocular tension
Dermatological/Allergic: rash,
urticaria, itching,
and other dermal manifestations; severe allergic
reaction or drug
idiosyncrasies including anaphylaxis.
Genitourinary: urinary hesitancy, urinary
retention
Cardiovascular: tachycardia. palpitations
Respiratory: Dyspnea, apnea,
asphyxia (see WARNINGS)
Other: decreased sweating, nasal
stuffiness or congestion, sneezing, throat
congestion, impotence. suppressron of lactation
(see PRECAUTIONS, Nursing
Mothers)
DRUG ABUSE AND DEPENDENCE
Abuse and/or dependence
on dicyclomine for anticholinergic
effects have been rarely reported.
DRUG INTERACTIONS
The following agents may increase certain actions or side
effects of anticholinergic drugs. amantadine antiarrhythmic
agents of class (e.g.
quinidine), antihistamines antipsychotic agents (e.g. phenothiazines),
benzodiazepines. MAO inhibitors,
narcotic analgesics
(e.g., meperidine), nitrates and nitrites, sympathomimetic
agents, tricyclic antidepressants, and other drugs having anticholinergic
activity.
Anticholinergics antagonize the effects of antiglaucoma agents.
Anticholinergic drugs in the presence of increased intraocular
pressure may be hazardous
when taken concurrently with agents such
as corti costeroids. (See also CONTRAINDICATIONS).
Anticholinergic agents may affect
gastrointestinal
absorption of various
drugs, such as slowly dissolving
dosage forms of digoxin;
increased serum digoxin concentrations may result.
Anticholinergic drugs may antagonize the effects of the drugs that
alter gastrointestinal motility,
such as metoclopramide.
Because antacids may interfere with the absorption
of anticholinergic
agents, simultaneous use of these drugs should be avoided.
The inhibiting effects of anticholinergic
drugs on gastric hydrochloric
acid secretion are
antagonized by agents used to treat achlorhydria
and those used to test
gastric secretion.
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